Liposome-encapsulated daunorubicin for PGP-related multidrug resistance
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چکیده
منابع مشابه
Liposome encapsulated daunorubicin (daunoxome) for acute leukemia.
Haematologica vol. 85(3):March 2000 7. Dunphy CH, Gregowicz AJ, Rodriguez G Jr. Natural killer cell acute leukemia with myeloid antigen expression. A previously undescribed form of acute leukemia. Am J Clin Pathol 1995; 104:212-5. 8. Nagata T, Higashigawa M, Nagai M, et al. A child case of CD34+, CD33-, HLA-DR-, CD7+, CD56+ stem cell leukemia with thymic involvement. Leuk Res 1996; 20:983-5. 9....
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1. Forssen EA, Ross ME. Daunoxome treatment of solid tumors: preclinical and clinical investigations. J Liposome Res 1994; 4:481-512. 2. Money-Kyrle JE, Bates E, Ready J, Gazzard BG, Phillips RH, Boag FC. Liposomal daunorubicin in advanced Kaposi’s sarcoma: a phase II study. Clin Oncol 1993; 5:367-371. 3. Michieli M, Damiani D, Ermacora A, Masolini P, Michelutti A, Baccarani M. Liposome encapsu...
متن کاملOvercoming PGP-related multidrug resistance. The cyclosporine derivative SDZ PSC 833 can abolish the resistance to methoxy-morpholynil-doxorubicin.
BACKGROUND The results obtained so far in studies designed to neutralize P glycoprotein (PGP)-related multidrug resistance (MDR) by using MDR reversal agents, have not yet fulfilled the promise of the experiments which were performed in vitro. In order to improve PGP-related MDR neutralization, we tested in vitro the activity of the cyclosporine derivative SDZ PSC 833 (PSC) together with doxoru...
متن کاملIncreased expression of multidrug resistance related proteins Pgp, MRP1, and LRP/MVP occurs early in colorectal carcinogenesis.
AIM To analyse the expression of multidrug resistance (MDR) related proteins at different steps in colorectal carcinogenesis. METHODS The presence of three MDR related proteins (Pgp, MRP1, and LRP/MVP) was studied by means of immunohistochemistry in normal, adenomatous, and malignant colorectal epithelium. Formaldehyde fixed, paraffin embedded tissue sections of 17 samples of colorectal tissu...
متن کاملIn Vitro Bactericidal Activity of Encapsulated Amikacin in Liposome
Background and Objectives: The most common problems limiting the medical use of aminoglycosides have been the nephro- and oto-toxicities as well as the increasing bacterial resistance. Encapsulation of drugs into liposomes enhances their efficacy while reducing their toxicities. The aim of this study was to evaluate the antimicrobial activity of free and liposomal amikacin. Material and Metho...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 1999
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.1999.01505.x